This volume provides an authoritative, up-to-date account of the impact of molecular genetics on our understanding of genetic diseases prevalent among Jews. The extent of genetic variability among different Jewish communities is discussed in detail. After an introductory chapter on major demographic trends of world Jewry, the first part examines ethnohistorical relationships between different Jewish groups in light of nuclear and mictochondrial DNA polymorphisms. The next and largest section of the book reviews the most recent research on some 20 Mendelian disorders (among Ashkenz, Sephardi and Oriental Jews) and the implications of the astonishing molecular heterogeneity revealed in some of them. Advances in genetic aspects of common multifactorial diseases are covered in concluding chapters.
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Batsheva Bonne-Tamir is at Sackler School of Medicine, Tel-Aviv University. Avinoam Adam is at The Open University of Israel.Review:
"Each chapter was well written, clear, and comprehensible for anyone with a background in college genetics and molecular genetics. All subjects in the book were thoroughly discussed. I would recommend this as an excellent resource book on the genetics of the Jewish people." --Applied
"A valuable addendum to the shelves of the comprehensive medical genetics library. It is beautifully produced, lovingly edited, and, for its type, modestly priced. Specialist and non-specialist could spend many happy hours browsing through the wealth of fascinating detail." --Genetical
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Descripción Oxford University Press, USA, 1992. Hardcover. Estado de conservación: New. 1. Nº de ref. de la librería DADAX0195068173
Descripción Oxford University Press, 1992. Hardcover. Estado de conservación: New. book. Nº de ref. de la librería M0195068173