Ligand Efficiency Indices for Drug Discovery: Towards an Atlas-Guided Paradigm

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9780124046351: Ligand Efficiency Indices for Drug Discovery: Towards an Atlas-Guided Paradigm
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"For those interested in a fresh interpretation of the utility of ligand efficiency indexes for drug discovery, this book serves as a nice introduction to a more modern, graphical approach to drug lead identification."--Doody.com, August 16, 2013 "Abad-Zapatero presents a novel approach to drug discovery that is based on the notion that a change of variables is necessary. The algebraic framework he proposes combines the affinity between ligands and targets with the physico-chemical properties of the ligands to construct a set of novel variables that can map chemico-biological space (CBS) and optimize the drug-discovery process."--Reference and Research Book News, August 2013

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The purpose of "Ligand Efficiency Indices for Drug Discovery: Towards an Atlas-Guided Paradigm" is to introduce in a concise and self-contained form the concepts, ideas, applications and examples of efficiency-driven drug discovery to the biomedical community at large. The book emphasizes the use of 'new variables' and more objective numerical methods to drive drug discovery in an encompassing way. These 'new variables' are based on Ligand Efficiency Indices (LEIs) formulated in a way that permits mapping Chemico-Biological Space (CBS) in an Atlas-like representation. It provides a practical and timely discussion of the concepts, ideas, applications and examples of efficiency-driven drug discovery. This book emphasizes the use of a graphical representation and objective numerical methods to drive drug discovery more effectively. It presents the definition of LEIs and the corresponding efficiency planes within an atlas-like environment to provide a robust graphical and numerical framework for medicinal chemists and drug-discoverers. It provides a practical and timely discussion of the concepts, ideas, applications and examples of efficiency-driven drug discovery. It emphasizes the use of 'new variables' and more objective numerical methods to drive quicker and more effective drug discovery. It presents the definition of Ligand Efficiency Indices (LEIs) and the corresponding efficiency planes as key concepts to provide a graphical and numerical framework.

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1.

Celerino Abad-Zapatero
Editorial: Elsevier Science Publishing Co Inc, United States (2013)
ISBN 10: 0124046355 ISBN 13: 9780124046351
Nuevos Paperback Cantidad: 1
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The Book Depository
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Descripción Elsevier Science Publishing Co Inc, United States, 2013. Paperback. Estado de conservación: New. 228 x 152 mm. Language: English . Brand New Book. The purpose of Ligand Efficiency Indices for Drug Discovery: Towards an Atlas-Guided Paradigm is to introduce in a concise and self-contained form the concepts, ideas, applications and examples of efficiency-driven drug discovery to the biomedical community at large. The book emphasizes the use of new variables and more objective numerical methods to drive drug discovery in an encompassing way. These new variables are based on Ligand Efficiency Indices (LEIs) formulated in a way that permits mapping Chemico-Biological Space (CBS) in an Atlas-like representation. It provides a practical and timely discussion of the concepts, ideas, applications and examples of efficiency-driven drug discovery. This book emphasizes the use of a graphical representation and objective numerical methods to drive drug discovery more effectively. It presents the definition of LEIs and the corresponding efficiency planes within an atlas-like environment to provide a robust graphical and numerical framework for medicinal chemists and drug-discoverers. Nº de ref. de la librería AAZ9780124046351

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Cele Abad Zapatero
ISBN 10: 0124046355 ISBN 13: 9780124046351
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Descripción Paperback. Estado de conservación: New. Not Signed; The purpose of Ligand Efficiency Indices for Drug Discovery: Towards an Atlas-Guided Paradigm is to introduce in a concise and self-contained form the concepts, ideas, applications and examples of efficiency-driven drug discovery to the biomedical community at large. The book emphasizes the use of '. book. Nº de ref. de la librería ria9780124046351_rkm

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Celerino Abad-Zapatero
Editorial: Elsevier Science Publishing Co Inc, United States (2013)
ISBN 10: 0124046355 ISBN 13: 9780124046351
Nuevos Paperback Cantidad: 1
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The Book Depository US
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Descripción Elsevier Science Publishing Co Inc, United States, 2013. Paperback. Estado de conservación: New. 228 x 152 mm. Language: English . Brand New Book. The purpose of Ligand Efficiency Indices for Drug Discovery: Towards an Atlas-Guided Paradigm is to introduce in a concise and self-contained form the concepts, ideas, applications and examples of efficiency-driven drug discovery to the biomedical community at large. The book emphasizes the use of new variables and more objective numerical methods to drive drug discovery in an encompassing way. These new variables are based on Ligand Efficiency Indices (LEIs) formulated in a way that permits mapping Chemico-Biological Space (CBS) in an Atlas-like representation. It provides a practical and timely discussion of the concepts, ideas, applications and examples of efficiency-driven drug discovery. This book emphasizes the use of a graphical representation and objective numerical methods to drive drug discovery more effectively. It presents the definition of LEIs and the corresponding efficiency planes within an atlas-like environment to provide a robust graphical and numerical framework for medicinal chemists and drug-discoverers. Nº de ref. de la librería AAZ9780124046351

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Celerino Abad-Zapatero
Editorial: Elsevier Science Publishing Co Inc
ISBN 10: 0124046355 ISBN 13: 9780124046351
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Descripción Elsevier Science Publishing Co Inc. Paperback. Estado de conservación: new. BRAND NEW, Ligand Efficiency Indices for Drug Discovery: Towards an Atlas-Guided Paradigm, Celerino Abad-Zapatero, The purpose of "Ligand Efficiency Indices for Drug Discovery: Towards an Atlas-Guided Paradigm" is to introduce in a concise and self-contained form the concepts, ideas, applications and examples of efficiency-driven drug discovery to the biomedical community at large. The book emphasizes the use of 'new variables' and more objective numerical methods to drive drug discovery in an encompassing way. These 'new variables' are based on Ligand Efficiency Indices (LEIs) formulated in a way that permits mapping Chemico-Biological Space (CBS) in an Atlas-like representation. It provides a practical and timely discussion of the concepts, ideas, applications and examples of efficiency-driven drug discovery. This book emphasizes the use of a graphical representation and objective numerical methods to drive drug discovery more effectively. It presents the definition of LEIs and the corresponding efficiency planes within an atlas-like environment to provide a robust graphical and numerical framework for medicinal chemists and drug-discoverers. It provides a practical and timely discussion of the concepts, ideas, applications and examples of efficiency-driven drug discovery. It emphasizes the use of 'new variables' and more objective numerical methods to drive quicker and more effective drug discovery. It presents the definition of Ligand Efficiency Indices (LEIs) and the corresponding efficiency planes as key concepts to provide a graphical and numerical framework. Nº de ref. de la librería B9780124046351

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Abad-Zapatero, Celerino
Editorial: Academic Press (2013)
ISBN 10: 0124046355 ISBN 13: 9780124046351
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Descripción Academic Press, 2013. Estado de conservación: New. 2013. 1st Edition. Paperback. Emphasizes the use of 'new variables' and objective numerical methods to drive drug discovery in an encompassing way. This book provides a practical discussion of the concepts, ideas, applications and examples of efficiency-driven drug discovery. Num Pages: 178 pages, Illustrated. BIC Classification: MMGT; PNN; TCB. Category: (P) Professional & Vocational. Dimension: 229 x 154 x 12. Weight in Grams: 386. Towards an Atlas-Guided Paradigm. 178 pages, Illustrated. Emphasizes the use of 'new variables' and objective numerical methods to drive drug discovery in an encompassing way. This book provides a practical discussion of the concepts, ideas, applications and examples of efficiency-driven drug discovery. Cateogry: (P) Professional & Vocational. BIC Classification: MMGT; PNN; TCB. Dimension: 229 x 154 x 12. Weight: 386. . . . . . . Nº de ref. de la librería V9780124046351

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Abad-Zapatero, Celerino
Editorial: Academic Press
ISBN 10: 0124046355 ISBN 13: 9780124046351
Nuevos Tapa blanda Cantidad: 4
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Kennys Bookstore
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Descripción Academic Press. Estado de conservación: New. 2013. 1st Edition. Paperback. Emphasizes the use of 'new variables' and objective numerical methods to drive drug discovery in an encompassing way. This book provides a practical discussion of the concepts, ideas, applications and examples of efficiency-driven drug discovery. Num Pages: 178 pages, Illustrated. BIC Classification: MMGT; PNN; TCB. Category: (P) Professional & Vocational. Dimension: 229 x 154 x 12. Weight in Grams: 386. Towards an Atlas-Guided Paradigm. 178 pages, Illustrated. Emphasizes the use of 'new variables' and objective numerical methods to drive drug discovery in an encompassing way. This book provides a practical discussion of the concepts, ideas, applications and examples of efficiency-driven drug discovery. Cateogry: (P) Professional & Vocational. BIC Classification: MMGT; PNN; TCB. Dimension: 229 x 154 x 12. Weight: 386. . . . . . Books ship from the US and Ireland. Nº de ref. de la librería V9780124046351

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Celerino Abad-Zapatero
Editorial: Elsevier Science Publishing Co Inc 2013-01-28, San Diego (2013)
ISBN 10: 0124046355 ISBN 13: 9780124046351
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Descripción Elsevier Science Publishing Co Inc 2013-01-28, San Diego, 2013. paperback. Estado de conservación: New. Nº de ref. de la librería 9780124046351

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Abad-Zapatero, Celerino
Editorial: Academic Press (2013)
ISBN 10: 0124046355 ISBN 13: 9780124046351
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Descripción Academic Press, 2013. Estado de conservación: New. Nº de ref. de la librería GH9780124046351

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Abad-Zapatero, Celerino
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Descripción Estado de conservación: New. Depending on your location, this item may ship from the US or UK. Nº de ref. de la librería 97801240463510000000

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Abad-Zapatero, Celerino
Editorial: Academic Press (2013)
ISBN 10: 0124046355 ISBN 13: 9780124046351
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Irish Booksellers
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Descripción Academic Press, 2013. Paperback. Estado de conservación: New. book. Nº de ref. de la librería 0124046355

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