Gene Therapy of Cancer: Translational Approaches from Preclinical Studies to Clinical Implementation

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9780123942951: Gene Therapy of Cancer: Translational Approaches from Preclinical Studies to Clinical Implementation
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"The Third Edition.provides crucial updates on the basic and applied sciences of gene therapy. It offers a comprehensive assessment of the field including the areas of suicide gene therapy, oncogene and suppressor gene targeting, immunotherapy, drug resistance gene therapy, and the genetic modification of stem cells."--Anticancer Research 34, 2014 "Gene therapy for cancer encompasses reforming genes gone bad, using gene expression to alter the function of both tumor and microenvironment, increasing the sensitivity of cancer cells to killer drugs, and protecting normal cells from such therapies. The studies here cover viral and non-viral vector methodologies: targets and approaches, oncolytic viruses, immunotherapeutics, drug resistance and metabolism gene therapy, cancer therapy imaging vectors, and issues in trail design review and approval."--Reference & Research Book News, December 2013

Críticas:

"Gene therapy for cancer encompasses reforming genes gone bad, using gene expression to alter the function of both tumor and microenvironment, increasing the sensitivity of cancer cells to killer drugs, and protecting normal cells from such therapies. The studies here cover viral and non-viral vector methodologies: targets and approaches, oncolytic viruses, immunotherapeutics, drug resistance and metabolism gene therapy, cancer therapy imaging vectors, and issues in trail design review and approval."--Reference & Research Book News, December 2013

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Editorial: Elsevier Science Publishing Co Inc, United States (2013)
ISBN 10: 0123942950 ISBN 13: 9780123942951
Nuevos Tapa dura Cantidad: 10
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The Book Depository
(London, Reino Unido)
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Descripción Elsevier Science Publishing Co Inc, United States, 2013. Hardback. Estado de conservación: New. 3rd Revised edition. 277 x 221 mm. Language: English . Brand New Book. Gene therapy as a treatment for cancer is at a critical point in its evolution. Exciting new developments in gene targeting and vector technology, coupled with results from the first generation of preclinical and clinical studies have led to the design and testing of new therapeutic approaches. The Third Edition of Gene Therapy of Cancer provides crucial updates on the basic and applied sciences of gene therapy. It offers a comprehensive assessment of the field including the areas of suicide gene therapy, oncogene and suppressor gene targeting, immunotherapy, drug resistance gene therapy, and the genetic modification of stem cells. Researchers at all levels of development, from basic laboratory investigators to clinical practitioners, will find this book to be instructive. Cancer gene therapy, like cancer therapy in general, is evolving rapidly, testing new concepts, targets and pathways, evoking new technologies, and passing new regulatory hurdles. Its essence, however, has not changed: the hope and challenges of returning altered genes to normal, using targeted gene expression to alter the function of both tumor and microenvironment, and in some cases normal cells, and delivering functionally important genes to specific cell types to increase sensitivity to killing or to protect normal cells from cancer therapies. In some instances, gene therapy for cancer forms a continuum from gene repair through the use of molecularly modified cells; the use of viral and non-viral vector based gene delivery to both tumor and tumor microenvironment; the use of viral and gene based vaccines; and development of new gene-based therapeutics. The unique mechanistically chosen vector platforms are at the heart of this technology because they allow for direct and selective cell death and transient to sustained delivery of vaccine molecules or molecules that affect the microenvironment, vasculature, or the immune response. Nº de ref. de la librería AA59780123942951

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Edmund Lattime
Editorial: Academic Press 2013-10-14 (2013)
ISBN 10: 0123942950 ISBN 13: 9780123942951
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Chiron Media
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Descripción Academic Press 2013-10-14, 2013. Hardcover. Estado de conservación: New. Nº de ref. de la librería NU-ELS-00004423

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Editorial: Elsevier Science Publishing Co Inc, United States (2013)
ISBN 10: 0123942950 ISBN 13: 9780123942951
Nuevos Tapa dura Cantidad: 10
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The Book Depository US
(London, Reino Unido)
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Descripción Elsevier Science Publishing Co Inc, United States, 2013. Hardback. Estado de conservación: New. 3rd Revised edition. 277 x 221 mm. Language: English . Brand New Book. Gene therapy as a treatment for cancer is at a critical point in its evolution. Exciting new developments in gene targeting and vector technology, coupled with results from the first generation of preclinical and clinical studies have led to the design and testing of new therapeutic approaches. The Third Edition of Gene Therapy of Cancer provides crucial updates on the basic and applied sciences of gene therapy. It offers a comprehensive assessment of the field including the areas of suicide gene therapy, oncogene and suppressor gene targeting, immunotherapy, drug resistance gene therapy, and the genetic modification of stem cells. Researchers at all levels of development, from basic laboratory investigators to clinical practitioners, will find this book to be instructive. Cancer gene therapy, like cancer therapy in general, is evolving rapidly, testing new concepts, targets and pathways, evoking new technologies, and passing new regulatory hurdles. Its essence, however, has not changed: the hope and challenges of returning altered genes to normal, using targeted gene expression to alter the function of both tumor and microenvironment, and in some cases normal cells, and delivering functionally important genes to specific cell types to increase sensitivity to killing or to protect normal cells from cancer therapies. In some instances, gene therapy for cancer forms a continuum from gene repair through the use of molecularly modified cells; the use of viral and non-viral vector based gene delivery to both tumor and tumor microenvironment; the use of viral and gene based vaccines; and development of new gene-based therapeutics. The unique mechanistically chosen vector platforms are at the heart of this technology because they allow for direct and selective cell death and transient to sustained delivery of vaccine molecules or molecules that affect the microenvironment, vasculature, or the immune response. Nº de ref. de la librería AA59780123942951

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Lattime, Edmund C. (Editor)/ Gerson, Stanton L. (Editor)
Editorial: Academic Pr (2013)
ISBN 10: 0123942950 ISBN 13: 9780123942951
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Revaluation Books
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Descripción Academic Pr, 2013. Hardcover. Estado de conservación: Brand New. 3rd edition. 537 pages. 10.75x8.75x1.25 inches. In Stock. Nº de ref. de la librería __0123942950

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LATTIME, EDMUND; GERSON, STANTON
Editorial: Academic Press (2013)
ISBN 10: 0123942950 ISBN 13: 9780123942951
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Herb Tandree Philosophy Books
(Stroud, GLOS, Reino Unido)
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Descripción Academic Press, 2013. Hardback. Estado de conservación: NEW. 9780123942951 This listing is a new book, a title currently in-print which we order directly and immediately from the publisher. Nº de ref. de la librería HTANDREE0893453

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LATTIME, EDMUND; GERSON, STANTON
Editorial: Academic Press (2013)
ISBN 10: 0123942950 ISBN 13: 9780123942951
Nuevos Tapa dura Cantidad: 1
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Herb Tandree Philosophy Books
(Stroud, GLOS, Reino Unido)
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Descripción Academic Press, 2013. Hardback. Estado de conservación: NEW. 9780123942951 This listing is a new book, a title currently in-print which we order directly and immediately from the publisher. Nº de ref. de la librería HTANDREE01197368

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Editorial: Academic Press (2013)
ISBN 10: 0123942950 ISBN 13: 9780123942951
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Irish Booksellers
(Rumford, ME, Estados Unidos de America)
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Descripción Academic Press, 2013. Hardcover. Estado de conservación: New. book. Nº de ref. de la librería 0123942950

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