Handbook of the Biology of Aging, Seventh Edition (Handbooks of Aging)

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9780123786388: Handbook of the Biology of Aging, Seventh Edition (Handbooks of Aging)

Handbook of the Biology of Aging, Seventh Edition, reviews and synthesizes recent findings and discoveries in the field. This volume is part of The Handbooks of Aging series, which also includes The Handbook of the Psychology of Aging and The Handbook of Aging and the Social Sciences.
The book is organized into two parts. Part 1 covers basic aging processes. It covers concepts relevant to clinical research, such as muscle, adipose tissue, and stem cells. It discusses research on how dietary restriction can slow down the aging process and extend life in a wide range of species. Part 2 deals with the medical physiology of aging. It contains several chapters on the aging of the human brain. These chapters deal not only with diseases but also with normal aging changes to cerebral vasculature and myelination as well as the clinical implications of those changes. Additional chapters cover how aging affects central features of human health such as insulin secretion, pulmonary and cardiac function, and the ability to maintain body weight and body temperature.
The volume is primarily directed at basic researchers who wish to keep abreast of new research outside their own subdiscipline. It will also be useful to medical, behavioral, and social gerontologists who want to learn about the discoveries of basic scientists and clinicians.

  • Contains basic aging processes as determined by animal research as well as medical physiology of aging as known in humans
  • Covers hot areas of research, like stem cells, integrated with longstanding areas of interest in aging like telomeres, mitochondrial function, etc.
  • Edited by one of the fathers of gerontology (Masoro) and contributors represent top scholars in gerintology

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From the Back Cover:

Handbook of the Biology of Aging, 7th edition

Edited by Edward J. Masoro and Steven N. Austad

The Handbook of the Biology of Aging, 7e, is 100% revised from the 6th edition.  Providing a comprehensive synthesis and review of the latest research findings in the biology of aging, it is intended as a summary for researchers, and is also suitable as a high level textbook for graduate and upper level undergraduate courses.  The 7th edition is organized into two main sections, first covering the basic aging processes and then the medical physiology of aging.  This puts less emphasis on research germane only to specific species and more emphasis on the mechanisms that affect aging across species, and what this means medically for the aging of humans.  This volume allows basic researchers to keep abreast of basic research outside their subdiscipline as well as recent clinical  findings, while allowing medical, behavioral, and social gerontologists to understand what basic scientists and clinicians are discovering.

Coverage of basic aging processes includes the effects of dietary restriction, somatotropic axis, free radicals, apoptosis, adipose tissue, stem cells, leukocyte telomere dynamics, genetics, sirtuins, inflammation, and protein homeostasis on aging.  Coverage of the medical physiology of aging includes several chapters on aging effects on the human brain including changes in brain myelination, cerebral microvasculature, and cerebral vascular dysfunction.    Additional chapters include research on aging pulmonary function, insulin secretion, thermoreception and thermoregulation, calorie restriction, frailty & mortality, and sex differences in longevity and aging.  This more clinically-oriented section advances our understanding  of what to expect, how to prevent, and how to treat common medical effects of aging.

The Handbook of the Biology of Aging, 7e is part of the Handbooks of Aging series, including Handbook of the Psychology of Aging and Handbook of Aging and the Social Sciences, also in their 7th editions.

About the editors:

Dr Edward J Masoro is professor emeritus in the department of physiology at University of Texas Health Science Center San Antonio.  In addition to being the recipient of numerous award for his work in gerontology, he is a past president of the Gerontological Association of America, has served as chairman of both the Aging Review Committee and Board of Scientific Counselors of the National Institute on Aging, and is former editor of the Journal of Gerontology:  biological Sciences.

Dr. Steven N. Austad is professor in the department of cellular and structural biology at the University of Texas Health Science Center San Antonio.  In addition to being the recipient of numerous awards for his work in gerontology, he is currently associate editor of the Journal of Gerontology:  Biological Sciences, supervising editor of Aging Cell, and section editor of The Neurobiology of Aging.

About the Author:

Edward J. Masoro was the recipient of the 1989 Allied-Signal Achievement Award in Aging Research. In 1990, he received the Geriatric Leadership Academic Award from the National Institute on Aging and the Robert W. Kleemeier Award from the Gerontological Society of America. In 1991, he received a medal of honor from the University of Pisa for Achievements in Gerontology. In 1993, Dr. Masoro received the Distinguished Service Award from the Association of Chairmen of Departments of Physiology. He received the 1995 Irving Wright Award of Distinction of the American Federation for Aging Research and the 1995 Glenn Foundation Award. He served as the President of the Gerontological Society of America from 1994-1995, as the Chairman of the Aging Review Committee of the National Institute on Aging (NIA), and as Chairman of the Board of Scientific Counselors of the NIA. Dr. Masoro received his Ph.D. from the University of California at Berkeley. He has held faculty positions at Queens University (Canada), Tufts University School of Medicine, University of Washington,and Medical College of Pennsylvania. From 1973 through May 1991, he served as Chairman of the Department of Physiology at the University of Texas Health Science Center at San Antonio. He presently continues his duties as Professor in the Department of Physiology and is the Director of the newly created Aging Research and Education Center. On April 1, 1996, he became Professor Emeritus. Dr. Masoro was a Wellcome Visiting Professor in Basic Medical Sciences for the 1992-1993 Academic Year. His research has been in lipid metabolism, cold exposure, membrane biochemistry, and biological gerontology. Since 1975, Dr. Masoros research has focused on the influence of food restriction on aging. He has or is serving in an editorial role for ten journals, and in January 1992, he became the Editor of the Journal of Gerontology: Biological Sciences.

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