Stockley's Drug Interactions: A Source Book of Interactions, Their Mechanisms, Clinical Importance and Management - Tapa dura

Now in its tenth edition, Stockley's Drug Interactions is still the most indispensible and authoritative international source of drug interaction information. Based upon the many thousands of published clinical papers and reports, it provides a series of detailed, yet concise, monographs designed for quick and easy reference. Each monograph contains a summary, clinical evidence for the interaction under discussion, its probable mechanism, clinical importance, and management. Features: 1. Covers interactions between therapeutic drugs, proprietary medicines, some commonly used herbal medicines, foods, drinks, pesticides, and drugs of abuse. 2. Provides a comprehensive and fully-referenced discussion of the available clinical evidence for interactions, an assessment of their clinical importance, and gives clear practical guidance on how to manage the interaction, all in detailed yet concise monographs. 3. Content is clinically relevant, evaluated, and evidence-based, and provides the depth of critical information that is often missing from more general reference works. 4. Based on published sources and fully referenced. 5. Global coverage - inclusion of drugs used worldwide. 6 Part of a family of drug interactions resources including a quick reference pocket book, Stockley's Drug Interactions Pocket Companion, a specialist herbal interactions text, Stockley's Herbal Medicines Interactions, and Stockley's Drug Interactions Alerts, which contains data suitable for integration into dispensing and prescribing systems. New in this edition. The tenth edition has been comprehensively updated in-line with published literature and contains information on many new drugs, including amifampridine, dapoxetine, febuxostat, fingolimod, HCV- protease inhibitors (boceprevir and telaprevir), omalizumab, and tapentadol. Some highlights include: * Content has been updated to include new advice regarding the concurrent use of oral contraceptives and antibacterials; * Table of P-glycoprotein inhibitors has been revised and updated; * Tables of cytochrome P450 inducers and inhibitors have been revised and updated; * Table of drugs that prolong the QT-interval has been revised and updated.

Stockley’s Drug Interactions, edited by Karen Baxter and Claire L Preston, remains the world’s most comprehensive and authoritative reference book on drug interactions.· Covers interactions between therapeutic drugs, proprietary medicines, herbal medicines, foods, drinks and drugs of abuse · Contains detailed yet concise monographs in an easy-to-read format, each one including a brief summary of the interaction· Provides comprehensive details of the clinical evidence for the interactions under discussion, an assessment of their clinical importance, and gives clear guidance on how to manage the interaction in practice· Based on published sources and fully referenced· Contains almost 4,200 monographs· Global coverage – inclusion of drugs used worldwideFor the 10th edition · Over 400 new monographs added· Many existing monographs have been reviewed, revalidated and updated· Updated list of drugs that have a risk of prolonging the QT interval, and updates to the level of risk of QT-prolongation associated with these drugs· Fully revised classification tables of inhibitors, inducers, and substrates of CYP450 enzymes, based on clinical pharmacokinetic data· In-depth analysis of the supporting data and development of the table identifying drugs affected, or transported, by P-glycoprotein· Summary of the drugs suspected of causing serotonin syndrome