Sir Archibald Garrod had a distinguished career in medicine and maintained a lifelong interest in biochemistry. His first book, "Inborn Errors of Metabolism", was published in 1909 and established chemical individuality as the paradigm of Mendelian variation. In the years that followed, Garrod continued to develop the theme of the relationship between chemical individuality and disease and at the end of his career he wrote "Inborn Factors in Disease", in which he set out his belief that chemical individuality could result in individuals having a predisposition to certain diseases. This was published in 1931, but was not well received. Today, the importance of genetic disease is recognized and this work, which contains a complete facsimile reprint of the original text, now represents the origin of modern molecular medicine and genetics in medicine.
"Sobre este título" puede pertenecer a otra edición de este libro.
Descripción Oxford University Press, Oxford, 1989. Reprint of G&M 253.1. xiv, 248 p. 24 cm. Photo of the author, 5 b&w figures, 2 tables. Garrod pioneered the field of studying inborn "errors" or variations of metabolism. He was the first to connect a human disorder with Mendel's laws of inheritance. Ink stamp and ink notation on front free endpaper. Occasional pencil marginalia. Soiling to p. 170. Blue cloth hardcover with gold, red and blank impressing. In mylar-covered pictorial dustjacket. Nº de ref. de la librería 105248
Descripción Oxford, etc.: Oxford University Press, 1989., 1989. Hardcover. Estado de conservación: Fine. Estado de la sobrecubierta: Fine. 1st Edition. 1 leaf, xiv, 248 pp; portrait; figs. Original cloth. A couple of ink notes on title page -- this is not a proof copy, but they comment on the placement of the headers ('too high') and imprint ('too big') -- and one beside portrait ('this should face t/p'), else Near Fine, in near fine dust jacket. Oxford Monographs on Medical Genetics 16. Pp. 25-184 (160 pp in original edition) = Facsimile Reprint of Garrison-Morton 253.2 (1st ed., 1931): 'Garrod argued that chemical individuality could result in individuals having a predisposition to certain diseases. This view has become particularly significant in light of the establishment of recombinant DNA methods to identify inherited genetic defects. Reprint with epilogue by C.R. Scrivner and B. Childs, and bibliography of Garrod's writings, Oxford, Oxford University Press, 1989 [offered here].' Pp. v-viii = Foreword by Joshua Lederberg. Nº de ref. de la librería 18838
Descripción Oxford University Press, 1989. Estado de conservación: very good. Gently used. Expect delivery in 20 days. Nº de ref. de la librería 9780192615749-3